Question: Two diets are to be compared with regard to weight gain of weanling rats. i) What research design you would suggest for this study? What

Two diets are to be compared with regard to weight gain of weanling rats.

i) What research design you would suggest for this study? What type of study this is: Cohort, Observational or an Experimental study? Differentiate between these.

ii) If the weight gain due to the diets differs by 10 g or more, we would like to be 80% sure that we obtain a significant result. How many rats should be in each group if the s.d. is estimated to be 5 and the test is performed at the 5% level? How many rats per group would you use if the standard deviation were known to be equal to 5?

iii) What are various phases of a clinical trial?

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