Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be...
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Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column of length L = 65.0 cm containing N theoretical plates. The compounds have a separation factor (adjusted relative retention), a, of 1.009 and retention factors of 5.85 and 5.90, respectively. Calculate the number of theoretical plates, N, in the column of length L. The observed resolution is 1.74 after 15 cycles. N = Calculate the height of an individual plate in micrometers. H = Estimate the resolution after 3 cycles. resolution: plates um Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column of length L = 65.0 cm containing N theoretical plates. The compounds have a separation factor (adjusted relative retention), a, of 1.009 and retention factors of 5.85 and 5.90, respectively. Calculate the number of theoretical plates, N, in the column of length L. The observed resolution is 1.74 after 15 cycles. N = Calculate the height of an individual plate in micrometers. H = Estimate the resolution after 3 cycles. resolution: plates um
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N 3619 H 177 m Resolution 112 Explanation N 3619 The number of theoretical pl... View the full answer
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