Question: What do the parameters in the Gompertz model represent in the contextof the modeled tumor? If a treatment reduces the rate of tumor growth, will

What do the parameters in the Gompertz model represent in the contextof the modeled tumor? If a treatment reduces the rate of tumor growth, will that have a signif-icant impact on the long-term outcome of the cancer? What change(s)to the model would result in the prediction that the long-term outcomewould improve? How might this be effected? If we linearize the Gompertz model, what assumptions are we making?When is this approximation able to accurately predict the behavior ofthe full Gompertz model? What prediction does it make? To determine the behavior of a small tumor, what approximation to theGompertz equation might be appropriate? What type of behavior doesthis predict for the tumor? How is this similar to the prediction of theGompertz equation?

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