Question 11 Part A Which of the following statements about the oxyanion hole is NOT true?...

   

   

   

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Question 11 Part A Which of the following statements about the oxyanion hole is NOT true? It represents an enthalpic interaction that helps stabilize the transition state. O The backbone NH bonds of S195 and G193 create H-bonding interactions with the developing negative charge as Ser 195 attacks the scissile carbon bond. O This preformed loop is properly positioned to stabilize the negatively charged tetrahedral intermediate involved in amide bond hydrolysis. O It represents an electrostatic interaction that leads to a lower energy state. Submit My Answers Give Up Question 12 Part A Please match each cofactor with its function. 1) thiamine pyrophosphateA) CO2 activation/transfer 2) coenzyme A B) oxidation/reduction 3) biotin C) activation of aldehydes D) acyl group transfer 4) NAD+ 1:B; 2:C; 3:D; 4:A O 1:C; 2:D; 3:A; 4:B O 1:A; 2:D; 3:C; 4:B O 1:C; 2:B; 3:A; 4:D Submit My Answers Give Up Question 15 Part A Which of the following statements about the various methods of enzyme inhibition is NOT true? Irreversible inhibitors, primarily because they covalently modify an enzyme, are often toxic. Uncompetitive inhibitors bind at a different site than substrate but only after enzyme has bound its native target. Competitive inhibitors bind at a different site than substrate, altering the ability of the enzyme to bind its native target. Noncompetitive inhibitors bind at a different site than substrate, altering the ability of the enzyme to bind its native target. Submit My Answers Give Up Question 11 Part A Which of the following statements about the oxyanion hole is NOT true? It represents an enthalpic interaction that helps stabilize the transition state. O The backbone NH bonds of S195 and G193 create H-bonding interactions with the developing negative charge as Ser 195 attacks the scissile carbon bond. O This preformed loop is properly positioned to stabilize the negatively charged tetrahedral intermediate involved in amide bond hydrolysis. O It represents an electrostatic interaction that leads to a lower energy state. Submit My Answers Give Up Question 12 Part A Please match each cofactor with its function. 1) thiamine pyrophosphateA) CO2 activation/transfer 2) coenzyme A B) oxidation/reduction 3) biotin C) activation of aldehydes D) acyl group transfer 4) NAD+ 1:B; 2:C; 3:D; 4:A O 1:C; 2:D; 3:A; 4:B O 1:A; 2:D; 3:C; 4:B O 1:C; 2:B; 3:A; 4:D Submit My Answers Give Up Question 15 Part A Which of the following statements about the various methods of enzyme inhibition is NOT true? Irreversible inhibitors, primarily because they covalently modify an enzyme, are often toxic. Uncompetitive inhibitors bind at a different site than substrate but only after enzyme has bound its native target. Competitive inhibitors bind at a different site than substrate, altering the ability of the enzyme to bind its native target. Noncompetitive inhibitors bind at a different site than substrate, altering the ability of the enzyme to bind its native target. Submit My Answers Give Up

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Answer 1 The false statement of oxyanion hole It repre... View the full answer