Question: Which statement accurately compares GPCRs and RTKs ? GPCRs often activate multiple pathways, but RTKs only stimulate one ( or very few ) . Both
Which statement accurately compares GPCRs and RTKs
GPCRs often activate multiple pathways, but RTKs only stimulate one or very few
Both will become phosphorylated upon ligand binding.
Both have transmembrane spanning alpha helical segments
RTKs typically activate Gproteins, and GPCRs typically inhibit Gproteins.
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Most receptors, include GPCRs and RTKs mediate several cellular responses by activating or inhibiting several "pathways". These can be metabolic pathways or other
pathways important for cell growth, development, or motility.
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