Why is system integration important during regeneration?

Unlike embryogenesis, regeneration requires coordination between newly developing and existing structures.

Tissues must be isolated from existing structures in order to regenerate fully without inhibition.

All cells in a regenerating structure develop based on signals that they receive from existing structures, meaning that continual interaction of all new cells with surrounding cells is required.

System integration takes place during embryogenesis and regeneration generally follows the same sequence of events.