Question: You have identified three mutations (a, b and c) that cause loss of binding of a general processing factor and resulting processing defects in the
You have identified three mutations (a, b and c) that cause loss of binding of a general processing factor and resulting processing defects in the pre-mRNA in Heart or Skeletal Muscle as shown on the right. Wild- type processing is shown at the top for comparison. Horizontal lines over introns, marked by asterisks (*), indicate that the intron becomes included in the mature mRNA of the corresponding tissue
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