(a) The Monod equation describing microbial growth in a CSTR is given by the following mathematical...
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(a) The Monod equation describing microbial growth in a CSTR is given by the following mathematical formula: μ = Hmax Cs ks + Cs where μ is the specific growth rate (mol m-3 s-1), Hmax is the maximum specific growth rate (mol m-3 s-1), ks is a saturation constant (mol m-³) and Cs is the concentration of the limiting substrate (mol m-³). (i) Describe the information that can be gained from this formula and its limitations. (ii) Suggest a bioprocess scheme that this formula can describe. (b) A batch bioreactor at 37°C is used to perform a bioprocess. Assume you are using as nutrient source a complex mixture of sugars that requires an enzyme to be broken to glucose and other monomers. (i) Sketch and discuss the evolution of the biomass concentration as a function of time (ii) Sketch and discuss the evolution of the product concentration (antibiotic) as a function of time. (iii) Discuss how the productivity will be altered if the reactor temperature was increased to (i) 45°C and (ii) 67°C (a) The Monod equation describing microbial growth in a CSTR is given by the following mathematical formula: μ = Hmax Cs ks + Cs where μ is the specific growth rate (mol m-3 s-1), Hmax is the maximum specific growth rate (mol m-3 s-1), ks is a saturation constant (mol m-³) and Cs is the concentration of the limiting substrate (mol m-³). (i) Describe the information that can be gained from this formula and its limitations. (ii) Suggest a bioprocess scheme that this formula can describe. (b) A batch bioreactor at 37°C is used to perform a bioprocess. Assume you are using as nutrient source a complex mixture of sugars that requires an enzyme to be broken to glucose and other monomers. (i) Sketch and discuss the evolution of the biomass concentration as a function of time (ii) Sketch and discuss the evolution of the product concentration (antibiotic) as a function of time. (iii) Discuss how the productivity will be altered if the reactor temperature was increased to (i) 45°C and (ii) 67°C
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Financial and Managerial Accounting the basis for business decisions
ISBN: 978-1259692406
18th edition
Authors: Jan Williams, Susan Haka, Mark Bettner, Joseph Carcello
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