Question: You may use a calculator or spread sheet application to work on this quiz 5 pts 1 The prevalence of Hutchinson Guilford Progeria is 1

You may use a calculator or spread sheet application to work

You may use a calculator or spread sheet application to work on this quiz 5 pts 1 The prevalence of Hutchinson Guilford Progeria is 1 per 22 million individuals in Japan The disease is caused by a Mendelian dominant mutation The disease mimics premature aging and affected persons rarely live past 13 years old With an average mutation rate in this population estimated at 1 x 10 5 what is the predicted selection against this allele Explain your calculated result 1 sentence

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