Question: Your classmate borrowed your car for the night. When you see him the next day, he's obviously hung over, and you're concerned that he may
Your classmate borrowed your car for the night. When you see him the next day, he's obviously hung over, and you're concerned that he may have driven your vehicle while drunk. With a few discreet questions, you find out that he drank 4 shots of Tequila (!) at 10PM and drove your car home at 2AM the next day. Each shot is approximately 40 mL and the tequila was 80 proof (40% ethanol by volume). If you assume that the shots were drunk very quickly and rapidly absorbed, you may assume that your classmate began with 4 shots worth of alcohol in his central compartment at 10PM. If only you knew his clearance rate, you'd be able to calculate his blood alcohol level at 2AM! Conveniently enough, your classmate's brother took part in a study at UCSF that tested his alcohol clearance, which was kclearance = 0.97E-4 1/hr. Your classmate weighs 59 kg and your classmate's brother weighs 70 kg. With the exception of their different sizes, their bodies probably deal with ethanol in a fairly similar fashion. For ethanol, the volume of distribution Vd is 0.80 L/kg of body weight. For the density of ethanol, use 0.79 g/mL
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