Question: To whom has the diagnostic test been applied? It is possible that characteristics of the patients or stage and severity of the disease can infl

To whom has the diagnostic test been applied? It is possible that characteristics of the patients or stage and severity of the disease can infl uence the sensitivity of the test. For example, it is likely that a test for cancer will have greater sensitivity for advanced rather than early disease. Have the authors given enough information to enable us to be sure of the disease status?

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