Although methoxy is a strongly activating (and ortho, paradirecting) group, the meta positions in methoxybenzene (anisole) are
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Although methoxy is a strongly activating (and ortho, para–directing) group, the meta positions in methoxybenzene (anisole) are actually slightly deactivated toward electrophilic substitution relative to benzene. Explain.
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Organic Chemistry structure and function
ISBN: 978-1429204941
6th edition
Authors: K. Peter C. Vollhardt, Neil E. Schore
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