Suppose instead that the synonymous rate is three times that of the non synonymous rate. Formally, n = and s = 3. Estimate ,

Suppose instead that the synonymous rate is three times that of the non synonymous rate. Formally, λn = λ and λs = 3λ. Estimate λ, and compare with the values of λ found in Exercises 41 and 42.
Mutation rates differ depending on whether changing the nucleotide base changes the amino acid (non synonymous sites) or not (synonymous sites). A piece of DNA has 200 non synonymous sites with 12 mutations and 100 synonymous sites with 15 mutations. Our goal is to estimate the mutation rate.