Suppose we tested 200 diseased people. Find the significance and compare to the results with a sample

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Suppose we tested 200 diseased people. Find the significance and compare to the results with a sample size of 100.
The significance of deviations from the null hypothesis depends on the sample size. Conduct a x2 test for the following samples based on Example 8.7.1. Suppose that 20% of diseased people tested have a particular allele (this would, of course, vary in a series of real experiments), and that 13% of healthy people are known to have the allele.
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