Question: Synthetic polyglutamic acid exists as an a helix in solution at pH 2-3. When the pH of such a solution is gradually raised through the

Synthetic polyglutamic acid exists as an a helix in solution at pH 2-3. When the pH of such a solution is gradually raised through the addition of a base, a dramatic change in optical rotation takes place at pH 5. This change has been associated with the unfolding of the a helix and the formation of a random coil. What structural feature of polyglutamic acid and what chemical change can you suggest as an explanation of this transformation?

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