The compound shown below is the antiparasitic drug miltefosine.

(a) Is this compound a glycerophospholipid?
(b) How does miltefosine likely cross the parasite cell membrane?
(c) In what part of the cell would the drug tend to accumulate?
Explain.
(d) Miltefosine binds to a protein that also binds some sphingolipids and some glycerophospholipids. What feature common to all these compounds is recognized by the protein?
The protein does not bind triacylglycerols.

Transcribed Image Text:

CH3 (CH215-0-P-CH2-CH2-N(CH3 Miltefosine