The free energy-requiring step in the synthesis of ATP is not the formation of ATP from ADP

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The free energy-requiring step in the synthesis of ATP is not the formation of ATP from ADP and Pi (ΔG ≈ 0), but the release of tightly bound ATP. Explain why this is not inconsistent with the +30.5 kJ⋅mol-1 free energy of formation of ATP in solution.
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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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