Question: The reaction to form a phosphate-ester linkage between two nucleotides can be approximated as follows: Would you predict the formation of a dinucleotide from two

The reaction to form a phosphate-ester linkage between two nucleotides can be approximated as follows:
The reaction to form a phosphate-ester linkage between two nucleotides

Would you predict the formation of a dinucleotide from two nucleotides to be a spontaneous process?

sugar-0-_pT-OH + HO-CH2-sugar- > sugar o-P O-CH2 sugarH20

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