An article titled “Naturally Occurring Anticoagulants and Bone Marrow Transplantation:

An article titled “Naturally Occurring Anticoagulants and Bone Marrow Transplantation: Plasma Protein C Predicts the Development of Venoocclusive Disease of the Liver” (Blood) compared baseline values for antithrombin III with antithrombin II values 7 days after a bone marrow transplant for .45 patients. The differences were found to be nonsignificant. Suppose 17 of the differences were positive and 28 were negative.The null hypothesis is that the median difference is zero, and the alternative hypothesis is that the median difference is not zero. Use the 0.05 level of significance. Complete the test and carefully state your conclusion.

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