Question: Bacteriophage T4 has a linear double-stranded DNA genome, yet mapping many mutations, as shown in Figure 22.11, generates a circular linkage map. How might you

Bacteriophage T4 has a linear double-stranded DNA genome, yet mapping many mutations, as shown in Figure 22.11, generates a circular linkage map. How might you explain this discrepancy?

Sliding clamp Glaip loader DNA polyImerase dCMP hydroxymethylase 162 43 42 40 Helicase41 Primase-61 dCTPase-dUTPase-56 60 20 Helicase-dda 1dNMP kinase 39 60 Topoisomeras 0 Reference point 80 52 160 100 Single-stranded- 32 DNA binding proteirn 140 120 DNA ligase-30

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