Diphenhydramine can also be synthesized by heating bromo diphenyl methane with the amino alcohol shown here. Offer

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Diphenhydramine can also be synthesized by heating bromo diphenyl methane with the amino alcohol shown here. Offer a reason why the oxygen, rather than the nitrogen, of this compound acts as the nucleophile. What factor favors the N? What factor favors the O? Which factor is wining in thiscase?

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Organic Chemistry

ISBN: 978-0534389512

2nd Edition

Authors: Joseph M. Hornback

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