Question: Even though genetically engineered mosquitoes might be developed that do not allow the reproduction of malaria protozoa, these mosquitoes would have little, if any, immediate

Even though genetically engineered mosquitoes might be developed that do not allow the reproduction of malaria protozoa, these mosquitoes would have little, if any, immediate effect on the spread of the disease. Why should this be so?
What would have to happen for these mosquitoes to significantly affect the spread of malaria?

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