Explain why the filtrate becomes hypotonic as it flows through the ascending limb of the nephron loop.

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Explain why the filtrate becomes hypotonic as it flows through the ascending limb of the nephron loop. Also explain why the filtrate at the bend of the nephron loop (and the interstitial fluid of the deep portions of the medulla) is hypertonic.
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Human Anatomy and Physiology

ISBN: 978-0321927040

10th edition

Authors: Elaine N. Marieb, Katja Hoehn

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