Understanding the Complement System: Functions, Pathways, and Clinical Implications

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Biology - Immunology

letadla123oigko Created by 9 mon ago

Cards in this deck(20)

What is the main function of the complement system in the body, particularly in relation to extracellular pathogens?

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How is a pathogen killed directly in the complement system?

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Which of the following is NOT a role of complement factors in the body?

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How many complement proteins are involved in the classical complement pathway?

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What initiates the activation of the classical complement pathway?

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Which component of C1 binds to Fc regions of antibodies in the classical complement pathway?

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How does IgM differ from IgG in terms of activating complement?

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What happens when IgG binds to an antigenic surface in relation to complement activation?

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Which step in the classical pathway transforms the C3 convertase into a C5 convertase?

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What is the role of C5b in the terminal complement components assembly?

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What is the role of C9 components in the complement system?

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How is the classical complement pathway controlled in plasma?

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Which protein prevents the assembly of activated complement components or induces their dissociation?

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What triggers the synthesis of transcription factors C/EBPÎ´ and NF-IL6 for enhanced complement transcription?

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How does Erythrocyte complement receptor 1 (CR1) contribute to immune complex clearance?

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What is the purpose of measuring CH50 in complement activity detection?

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Which diseases are associated with elevated complement activity?

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What is the role of complement deficiencies in protecting against encapsulated bacteria?

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Which population has a higher prevalence of C9 deficiency in the complement system?

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How does a deficiency in a single complement component typically manifest?

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