Question: Mutations that inactivate p53 have a recessive phenotype, whereas mutations aecting Ras are dominant. Explain the dierence.

Mutations that inactivate p53 have a recessive phenotype, whereas mutations affecting Ras are dominant. Explain the difference.

Step by Step Solution

★★★★★

3.46 Rating (172 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock

A cell heterozygous for p53 could still make sufficient p53 from its one functional gene to carry o... View full answer

blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Document Format (1 attachment)

Word file Icon

811-M-S-B-C (787).docx

120 KBs Word File

Students Have Also Explored These Related Biochemistry Questions!

Q:

Gerald Rubin and Allan Spradling devised a method of introducing a transposon into Drosophila. This approach has been important for the transposon tagging of many Drosophila genes. They began with a...

Q:

In Drosophila, a recessive mutation called chocolate (c) causes the eyes to be darkly pigmented. The mutant phenotype is indistinguishable from that of an autosomal recessive mutation called brown...

Q:

In Drosophila, recessive mutations in the dorsalventral axis gene dorsal(dl) cause a dorsalized phenotype in embryos produced by dl/dlmothers; that is, no ventral structures develop. Predict the...

Q:

Many cells associated with a variety of cancers have mutations in the p 5 3 gene. Why are mutated tumor suppressor genes, like p 5 3 , considered recessive mutations? The wild - type p 5 3 protein...

Q:

Point mutations that inactivate the GTPase domain of Ras are observed in many cancers. In the presence of GTPase mutations will there be an increase or decrease in the amount GTP bound to Ras? ( 1 pt...

Q:

Specialized proteins called cell cycle regulators, such as p 5 3 and p 2 1 , regulate the progression of the cell cycle from one phase to the next. This progression through the checkpoints is...

Q:

Researchers aiming to understand the mechanisms of apoptosis conducted an experiment by injecting cytochrome c into the cytosol of two types of mammalian cells: normal cells and cells with mutations...

Q:

Proto - oncogenes are transformed into oncogenes by mutations that inactivate the function of the protein. Group of answer choices True False

Q:

Let's suppose a cell line has become malignant because it has accumulated mutations that inactivate two different tumor-suppressor genes. A researcher followed the protocol described in the...

Q:

Select the mechanism that explains the development of different types of cancers in LFS patients with mutations in the p 5 3 gene

Q:

Air flows steadily in a pipe at 300 kPa, 77C, and 25 m/s at a rate of 18 kg/min. Determine (a) The diameter of the pipe, (b) The rate of flow energy, (c) The rate of energy transport by mass, and (d)...

Q:

Michael plc is considering buying some equipment to produce a chemical named X14. The new equipment's capital cost is estimated at $100 million. If its purchase is approved now, the equipment can b...

Q:

Prada has ten milion shares oufstanding, generates free cash flows of 5 6 0 milion each year and has a cost of capital of 1 0 % . It also has $ 4 0 milion of cash on hand. Prada wants io deoide...

Q:

Which of the following costs would be charged to the product as a prime cost? A Component parts B Part-finished work C Primary packing materials D Supervisor wages

Q:

How has oxytocin been implicated in human behavior?

Q:

What types of experiments led to evidence regarding the effect of oxytocin and vasopressin on mammalian behavior?

Q:

Imagine we identify a gene that is directly responsible for the effects of vasopressin on male mammals, including humanswe will call it trust1that leads to the production of a vasopressin receptor in...

Q:

\f\fMatlab Instructions: First, enter the data and relevant equations into Matlab. *Tip: it might be easier to put the respective data set into just one matrix with multiple rows/columns; for...

Q:

Assuming you are working as a financial advisor for a large investment bank, you are required to present a written report to summarize the factors (such as business background, corporate management,...

Q:

Answer the following questions given the provided switch statements. What is the value of posAdj if curEst is 4 ?