One step in the gluconeogenesis pathway for the biosynthesis of glucose is the partial reduction of 3-phosphoglycerate
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One step in the gluconeogenesis pathway for the biosynthesis of glucose is the partial reduction of 3-phosphoglycerate to give glyceraldehydes 3-phosphate. The process occurs by phosphorylation with ATP to give 1, 3-bisphospho- glycerate, reaction with a thiol group on the enzyme to give an enzyme hound thioester, and reduction with NADH. Suggest mechanisms for all threereactions.
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In all of these reactions a nucleophile adds to either carbon or phosphorus to form an int...View the full answer
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