The hydrolysis of a biological thioester to the corresponding carboxylate is often more complex than the overall result might suggest. The conversion of succinyl CoA to succinate in the citric add cycle, for instance, occurs by initial formation of an acyl phosphate, followed by reaction with guano sine diphosphate (GDP, a relative of ADP) to give succinate and guano sine tri-phosphate (GTP, a relative of ATP). Suggest mechanisms for bothsteps.

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НОРО COAS Co2 co2 Succinyl CoA Acyl phosphate "OPOPO-Guanosine (GDP) "OPOPOPO-Guanosine CO2 Succinate GTP