Question: Pfizer would like to test the effectiveness of a new cholesterol medication it has recently developed. To test the effectiveness, the LDL cholesterol level of

Pfizer would like to test the effectiveness of a new cholesterol medication it has recently developed. To test the effectiveness, the LDL cholesterol level of 12 randomly selected individuals was measured before and after they took the medication. The data are shown as follows and can be found in the Excel file cholesterol. xlsx.

Person Before AfterPerson Before After 7 184 105 8 185 104 3

a. Using α = 0.01, perform a hypothesis test to determine if the average LDL level is more the 50 points lower for patients who have taken the new medication.

b. Approximate the p value using Table 5 in Appendix A and interpret the result.

c. Construct a 99% confidence interval to estimate the average difference in LDL levels for people before and after they take the medication.

d. Verify your results using Excel.

e. Identify the p value using Excel and interpret the result.

f. What assumptions need to be made in order to perform this procedure?

Person Before AfterPerson Before After 7 184 105 8 185 104 3 184 17 9 212 138 180 104 10 206 25 5 208 114 92 120 6 203 35 12 175121 187 196 144 146

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