Rearrange the order of the following statements to give a flow diagram showing the evolution of resistance to the antibiotic streptomycin by the bacterium Escherichia coli.

1. Most of the population of E. coli is resistant to streptomycin.

2. A mutation in a DNA triplet of a plasmid, changing TTT to TTG, gives an E. coli bacterium resistance to streptomycin.

3. The resistant bacterium divides and passes copies of the plasmid to its off spring.

4. Sensitive bacteria die in the presence of streptomycin as a selective agent.

5. The frequency of the mutated gene in the population increases.

6. The resistant bacterium has a selective advantage and survives.