Question: For Problem 3.14, obtain a 95% confidence interval for the odds ratio using (a) The Woolf (i.e., Wald) interval, (b) Cornfields exact approach, (c) the

For Problem 3.14, obtain a 95% confidence interval for the odds ratio using

(a) The Woolf (i.e., Wald) interval,

(b) Cornfield’s ‘exact” approach, (c) the profile likelihood. In each case, note the effect of the zero cell count. Summarize advantages and disadvantages of each approach.

Data from Prob. 3.14:

A study considered the effect of prednisolone on severe hypercalcaemia in women with metastatic breast cancer (B. Kristensen et al., J. Intern. Med. 232: 237–245, 1992). Of 30 patients, 15 were randomly selected to receive prednisolone. The other 15 formed a control group. Normalization in their level of serum-ionized calcium was achieved by 7 of the treated patients and none of the control group. Analyze whether results were significantly better for treatment than for control. Interpret.

Step by Step Solution

★★★★★

3.29 Rating (161 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock

a En... View full answer

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Categorical Data Analysis Questions!

The researchers also need to obtain precise estimates of the mean difference in systolic blood pressures for people who use the anti-inflammatory drug versus those who do not. a. Suppose the sample...

Problem 8 in Chapter 12 involved comparing straight-line regression fits of SBP on QUET for smokers and nonsmokers, and it was found that these straight lines could be considered parallel. Use...

For problem 8-50, construct a 95% confidence interval for the difference in stock performance. In problem "Strategizing for the future" is management lingo for sessions that help managers make better...

3.6 A study considered the effect of prednisolone on severe hypercalcemia in women with metastatic breast cancer (B. Kristensen et al., J. Intern. Med. 232: 237-245, 1992). Of 30 patients, 15 were...

Exercises Chapter 2 2.1 Marginal and conditional probability: The social mobility data from Section 2.5 gives a joint probability distribution on (Y1 , Y2 )= (father's occupation, son's occupation)....

Assessment & Evaluation in Higher Education Vol. 29, No. 1, February 2004 Academic procrastination and statistics anxiety Anthony JOnwuegbuzieDepartment of Educational Measurement and Research,...

Possible Multiple Choice Questions for the Exam. Focus on the topics discussed in class. Chapter 1 Multiple Choice Identify the choice that best completes the statement or answers the question. ____...

COVER PAGE STAT 608 Homework 05 Summer 2017 Please TYPE your name and email address below, then convert to PDF and attach as the first page of your homework upload. NAME: EMAIL: HOMEWORK NUMBER:...

As you review these studies, think about the differences in the study designs and approach to answering their respective research questions. Think about the strengths and limitations of each design....

You have two piles of different unknown radioactive substances: pile A with a mass of 200 g, and pile B with a mass of 100 g. Would it be possible for these two piles to have the same rate of...

The Repo 105 transactions reduced Lehmans net leverage ratio from 17.8 to 16.1 at the end of fiscal 2007. Do you believe that was a material difference? Why or why not?

For a sample of data where n = 7 given below: 8 3 10 6 4 13 5 a. Calculate the mean, median, and mode. b. Calculate the range, variance, standard deviation, and coefficient of variation. c. Calculate...

1.2. To say that the heritability of intelligence is about 50 percent means that 50 percent of a. an individuals intelligence is due to genetic factors. b. the similarities between two groups of...

A Danish study of individuals born at a Copenhagen hospital between 1959 and 1961 reported higher mean IQ scores for adults who were breast-fed for longer lengths of time as babies (E. Mortensen et...

A study published by the National Cancer Institute (V. Kirsh et al., 2005) reported on the effect of lycopene and tomato product intake on the risk of prostate cancer. The study followed the health...

A study followed patients for four years after they had a heart attack (K. Mukamal et al., Circulation, vol. 105, 2002, pp. 24762481). Patients were interviewed about their weekly caffeinated tea...

A Arm's preferred stock pays an annual dividend of $4. and the stock sells for $88 Flotation costs for new issuances of preferred stock are 6% of the stock value What is the after-tax cost of...

An investor sells 250 shares short at $28. The sale requires a margin deposit equal to 55 percent of the proceeds of the sale. If the investor closes the position at $37, what was the percentage...

Solve for the unknown interest rate in each of the following (Do not round intermediate calculations. Enter your answers as a percent rounded to 2 decimal places, e.g., 32.16.)