Starting with an equimolar mixture of lactate and NAD at 25C, calculate and plot the extent of the following reaction as a function of pH where R is a side group For this reaction at solution conditions, the apparent Gibbs energy change is rxn G 25 9 kJ Also determine the pH at which half the lacta...

Calculating the extent of the reaction as a function of pH We can use the HendersonHasselbalch equation to calculate the fraction of lactate that is d ...

Starting with an equimolar mixture of lactate and NAD+ at 25C, calculate and plot the extent of

Question:

Starting with an equimolar mixture of lactate and NAD+ at 25°C, calculate and plot the extent of the following reaction as a function of pH:

R-OC-CHOH-CH3 + NAD+ lactate R-OC-CO-CH3 + NADH + H+ pyruvate

where R is a side group. For this reaction at solution conditions, the apparent Gibbs energy change is Δ_rxnG = 25.9 kJ. Also determine the pH at which half the lactate will have reacted at equilibrium.

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