To prepare a dog of mass 1.5 kg for surgery, 150 mg of the anesthetic phenobarbitol is
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To prepare a dog of mass 1.5 kg for surgery, 150 mg of the anesthetic phenobarbitol is administered intravenously. The reaction in which the anesthetic is metabolized (decomposed in the body) is first order in phenobarbitol and has a half-life of 4.5 h. After about 2 h, the drug begins to lose its effect. However, the surgical procedure requires more time than had been anticipated. What mass of phenobarbitol must be re-injected to restore the original level of the anesthetic in the dog?
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Related Book For 
Chemical Principles The Quest For Insight
ISBN: 9781464183959
7th Edition
Authors: Peter Atkins, Loretta Jones, Leroy Laverman
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