For the DOS, we would like to manually calculate two two-category NRIs when medical burden is added to HAM-D in the prediction of depression, using

a) 0.5 and

b) the sample depression rate as the cut-point. For each cut-point, answer the following questions:

(a) Generate the classification-reclassification table separately for depressed and nondepressed subjects.

(b) What are the numbers of improvements and deteriorations for depressed and nondepressed subjects?

(c) Estimate the two-category NRIs.