A high rate of base-substitution mutations can result from a polymerases tendency to incorporate a mispaired nucleotide
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A high rate of base-substitution mutations can result from a polymerase’s tendency to incorporate a mispaired nucleotide or from its poor ability to incorporate the correct nucleotide. Use the following information about the catalytic efficiency (kcat/KM) of two error-prone polymerases to compare their ability to generate substitution mutations.
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To compare the ability of two errorprone polymerases Polymerase N and HIV reverse transcriptase to g...View the full answer
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Related Book For 
Fundamentals Of Biochemistry Life At The Molecular Level
ISBN: 9781118918401
5th Edition
Authors: Donald Voet, Judith G Voet, Charlotte W Pratt
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