What is an appropriate procedure to test the hypothesis that there is an association between blood pressure

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What is an appropriate procedure to test the hypothesis that there is an association between blood pressure and blood lead, while controlling for sex? 


Hypertension

A study was conducted in Wales relating blood-pressure and blood-lead levels [46]. It was reported that 4 of 455 men with blood-lead levels ≤11 μg/100 mL had elevated SBP (≥160 mm Hg), whereas 16 of 410 men with blood-lead levels ≥12 μg/100 mL also had elevated SBP. It was also reported that 6 of 663 women with blood-lead levels ≤11 μg/100 mL had elevated SBP, whereas 1 of 192 women with blood-lead levels ≥12 μg/100 mL had elevated SBP.

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