# In a study described in the article Hyaluronan Impairs Vascular Function and Drug Delivery in a Mouse Model of Pancreatic

## Question:

In a study described in the article “Hyaluronan Impairs Vascular Function and Drug Delivery in a Mouse Model of Pancreatic Cancer” (Gut 2013: 112–120), hyaluronan was depleted from mice using either PEGPH20 or an equal dose of a standard treatment. The vessel patency (%) for each mouse was recorded.

Use a rank-sum test (as did the article’s authors) to determine if PEGPH20 yields higher vessel patency than the standard treatment at the .05 level. Would you also reject the null hypothesis at the .01 level? Comment on these results in light of the fact that every PEGPH20 measurement is higher than every standard-treatment measurement.

## This problem has been solved!

Do you need an answer to a question different from the above? Ask your question!

## Step by Step Answer:

**Related Book For**

## Modern Mathematical Statistics With Applications

**ISBN:** 9783030551551

3rd Edition

**Authors:** Jay L. Devore, Kenneth N. Berk, Matthew A. Carlton

**Question Details**

Chapter #

**14**- Nonparametric MethodsSection: Exercises

Problem: 49

**View Solution**

Create a free account to access the answer

**Cannot find your solution?**

Post a FREE question now and get an answer within minutes.
* Average response time.