In a study described in the article Hyaluronan Impairs Vascular Function and Drug Delivery in a Mouse Model of Pancreatic
Question:
In a study described in the article “Hyaluronan Impairs Vascular Function and Drug Delivery in a Mouse Model of Pancreatic Cancer” (Gut 2013: 112–120), hyaluronan was depleted from mice using either PEGPH20 or an equal dose of a standard treatment. The vessel patency (%) for each mouse was recorded.
Use a rank-sum test (as did the article’s authors) to determine if PEGPH20 yields higher vessel patency than the standard treatment at the .05 level. Would you also reject the null hypothesis at the .01 level? Comment on these results in light of the fact that every PEGPH20 measurement is higher than every standard-treatment measurement.
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Step by Step Answer:
To determine if PEGPH20 yields higher vessel patency than the standard treatment you can use the Wilcoxon rank sum test also known as the Mann Whitney …View the full answer
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Related Book For 
Modern Mathematical Statistics With Applications
ISBN: 9783030551551
3rd Edition
Authors: Jay L. Devore, Kenneth N. Berk, Matthew A. Carlton
Question Details
Chapter #
14- Nonparametric Methods
Section: Exercises
Problem: 49
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Question Posted: August 28, 2023 06:16:25