The yeast two-hybrid method is a powerful molecular genetic method to identify a protcin(s) that interacts with a known protein or protein domain. You have isolated the glucocorticoid receptor (GR) and have evidence that it is a modular protein containing an activation domain, a DNA binding domain, and a second ligand-binding activation domain. Further analysis reveals that in pituitary cells, the protein is anchored in the cytoplasm in the absence of its hormone ligand, a result leading you to speculate that it binds to other inhibitory proteins. Describe how a two-hybrid analysis could be use J to identify the protein(s) with which GR interacts. How would you specifically identify the domain in the GR that binds the inhibitor(s)?