Treatment of cells with the drug brefeldin A (BfA) has the effect of decoating Golgi apparatus membranes,
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Treatment of cells with the drug brefeldin A (BfA) has the effect of decoating Golgi apparatus membranes, resulting in a cell in which the vast majority of Golgi proteins arc found in the ER. What inferences can be made from this observation regarding roles of coat proteins other than promoting vesicle formation? Predict what type of mutation in Arfl might have the same effect as treating cells with BFA.
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Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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