Tropomyosin, at 93 kd, sediments at 2.6S, whereas the 65-kd protein, hemoglobin, sediments at 4.3S. (The sedimentation

Question:

Tropomyosin, at 93 kd, sediments at 2.6S, whereas the 65-kd protein, hemoglobin, sediments at 4.3S. (The sedimentation coefficient S is a linear measure of the rate of sedimentation.) These two proteins are drawn to scale in Figure Q8–1. How is it that the bigger protein sediments more slowly than the smaller one? Can you think of an analogy from everyday experience that might help you with this problem?

Figure Q8-1

hemoglobin tropomyosin