What causes the mode of catalysis to change from general base to nucleophilic in the hydrolysis of

Question:

What causes the mode of catalysis to change from general base to nucleophilic in the hydrolysis of an ortho carboxyl-substituted phenyl acetate?

Fantastic news! We've Found the answer you've been seeking!

Step by Step Answer:

Related Book For book-img-for-question

Organic Chemistry

ISBN: 978-0131407480

4th edition

Authors: Paula Yurkanis Bruice

See More Books

Question Posted: Jun 26, 2020 08:10 AM

See More Questions

Whether the ortho-carboxyl substituent acts as an intramolecular general-base catalyst or as an intramolecular nucleophilic catalyst can be determined by carrying out the hydrolysis of aspirin with...
The deuterium kinetic isotope effect (kH2O/kD2O) for the hydrolysis of aspirin is 2.2. What does this tell you about the kind of catalysis exerted by the ortho-carboxyl substituent? (It is easier to...
The following reaction occurs by a mechanism involving general-base catalysis: Propose a mechanism for this reaction. base + CH,CH20H CH2OH
The accounting records for The Skate Shed, Inc., reflected the following amounts at the end of January 2018: Prepare The Skate Shed?s multistep income statement for the fiscal year ended January 31,...
Consider the titration of 25.0 mL of 0.010 0 M Sn 2+ by 0.050 0 M Tl 3+ in 1 M HCl, using Pt and saturated calomel electrodes to find the end point. (a) Write a balanced titration reaction. (b) Write...
The financial statements at the end of Network Realty, Inc.s first month of operations are shown below. By analyzing the interrelationships among the financial statements, fill in the proper amounts...
Frequently, sales managers use contests and recognition rewards to motivate the sales force. If sales managers understand salesperson performance, why is it necessary to employ these additional...
Following are sales and administrative cost data for Big Jack Burgers for the last four months: Administrative cost is a mixed cost, and sale is a potential cost driver. REQUIRED A. Using the...
Given the following coding: read (x); read (y); while x #y loop if x > y then x=x-y; else y=y-x; end if; end loop; gcd := x; a) Draw the flow graph. b) Calculate the cyclomatic complexity using THREE...
Jimmy owns a garden in which he has planted N trees in a row. After a few years, the trees have grown up and now they have different heights. Jimmy pays much attention to the aesthetics of his...
The rate constant for the uncatalyzed reaction of two molecules of glycine ethyl ester to form glycylglycine ethyl ester is 0.6 s -1 M -1 . In the presence of [Co(ethylenediamine) 2 ] 2+ , the rate...
Northern Switching Ltd. (NSL) is a manufacturer of digital switching equipment and systems. The company has total assets of approximately $784 million. Each of the following events occurred after the...
Boron trifluoride, B F 3 B F 3 , is a planar molecule with F B F F B F bond angles of 120 120 . It has the same symmetry operations as the mass and spring system in Problems 8 and 9, hence has...
What determines an ads visual and verbal persona?
Explain the different types of speakers and sounds used in television commercials?
How does magazine advertising build brand loyalty?
Why is direct mail often referred to as junk mail, and how can that perception be turned around?
Explain the strategy behind using newspaper in an IMC campaign.
Manz Property Management Company announced that in the year ended June 30, 2013, its earnings before taxes amounted to $1,478,936. Calculate its taxes using Exhibit 3.6?
If the joint cost function for two products is C(x, y) = xy2 + 1 dollars (a) Find the marginal cost (function) with respect to x. (b) Find the marginal cost with respect to y.
Draw a reaction-energy diagram for a two-step endothermic reaction with a rate-limiting second step.
Treatment of tert-butyl alcohol with concentrated HCl gives tert-butyl chloride. When the concentration of is doubled, the reaction rate doubles. When the concentration of tert-butyl alcohol is...
Label each hydrogen atom in the following compounds as primary (1°), secondary (2°), or tertiary (3°). (a) CH3 CH2 CH (CH3)2 (b) (CH3)3 CCH2CH3 (c) (CH3)2 CHCH (CH3) CH2 CH3 (d) (e) (f) ...
What are some scholarly sources that support the implementation of a case manager?
Review your own current processes relating to ER and IR within the organisation and identify three issues that can be improved upon.
A group of students working on a collaborative research project needs a centralized space to store and edit their documents. Which Teams feature should they primarily use?

What causes the mode of catalysis to change from general base to nucleophilic in the hydrolysis of

Question:

Step by Step Answer:

The hydrolysis of phenylacetate a nucleophilic substitution reaction can be catalyzed by th...View the full answer

Organic Chemistry

Students also viewed these Sciences questions