(a) For many years it was difficult to determine the X-ray structures of proteins that are imbedded...
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(a) For many years it was difficult to determine the X-ray structures of proteins that are imbedded in membranes because, when they are extracted into an aqueous buffer, they denature. Explain why this denaturation occurs.
(b) In some cases, this denaturation can be prevented by extraction of the protein from the membrane with detergents (Sec. 20.5). Explain.
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a A membrane is a very hydrophobic environment If a protein is embedded in a membrane then the surfa...View the full answer
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