Fluphenazine is an antipsychotic drug that is administered as an ester prodrug via intramuscular injection: The hydrophobic

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Fluphenazine is an antipsychotic drug that is administered as an ester prodrug via intramuscular injection:

CF3 Fluphenazine decanoate %24


The hydrophobic tail of the ester is deliberately designed to enable a slow release of the prodrug into the bloodstream, where the prodrug is rapidly hydrolyzed to produce the active drug.

(a) Draw the structure of the active drug

(b) Draw the structure of and assign a systematic name for the carboxylic acid that is produced as a by-product of the hydrolysis step.

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Organic Chemistry

ISBN: 978-0470917800

1st edition

Authors: David R. Klein

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