In Chapter 23, we will learn several methods for making primary amines (RNH 2 ). Each of

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In Chapter 23, we will learn several methods for making primary amines (RNH2). Each of these methods utilizes a different approach for forming the C€”N bond. One of these methods, called the Gabriel synthesis, forms the C€”N bond by treating potassium phthalimide with an alkyl halide:

Н N-R -R Н *NH2


The first step of this process occurs via an SN2 mechanism. Using this information, determine whether the Gabriel synthesis can be used to prepare the following amine. Explain your answer.

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Organic Chemistry

ISBN: 978-0470917800

1st edition

Authors: David R. Klein

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