Troglitazone, rosiglitazone, and pioglitazone, all antidiabetic drugs introduced to the market in the late 1990s, are believed
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(a) Based on these structures, try to identify the likely pharmacophore that is responsible for the antidiabetic activity of these drugs.
(b) Consider the structure of rivoglitazone (below). This compound is currently being studied for potential antidiabetic activity. Based on your analysis of the likely pharmacophore, do you believe that rivoglitazone will exhibit antidiabetic properties?
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