Question: In the hypergeometric polygenic model, suppose that one randomly samples each of the n polygenes transmitted to a gamete with replacement rather than without replacement.
In the hypergeometric polygenic model, suppose that one randomly samples each of the n polygenes transmitted to a gamete with replacement rather than without replacement. If j = i is not a descendant of i, and i has parents k and l, then show that this altered model entails E(Xi)=0 Cov(Xi, Xj ) = 1 2 Cov(Xk, Xj ) + 1 2 Cov(Xl, Xj )
Var(Xi)=2n +
1 4
1 − 1 n
Var(Xk) + 1 4
1 − 1 n
Var(Xl)
+
1 2 Cov(Xk, Xl).
Step by Step Solution
There are 3 Steps involved in it
Get step-by-step solutions from verified subject matter experts
