Recall the Central Dogma for biology, which is depicted in simplified form in the block diagram Fig.

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Recall the Central Dogma for biology, which is depicted in simplified form in the block diagram Fig. E24.7. In this case, it is assumed that nuclear transport can be ignored. Let X denote an environmental perturbation to the system.

Gp G. Ga Figure E24.7 (a) Explain briefly the biological process denoted by Ga, Gb, Gc, and the variable Y.

(b) Find a general expression for Y(s)/X(s), that is, the overall closed-loop transfer function. It should be simplified to contain only a numerator expression and a denominator expression without additional fractions.

(c) Consider now the specific values for the biological processes: Ga = 5, Gb = 0.5/s, and Gc = 3/s. Evaluate your expression from part (b) for this case and simplify accordingly. Is the closed-loop stable?

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Process Dynamics and Control

ISBN: 978-1119385561

4th edition

Authors: Dale E. Seborg, Thomas F. Edgar, Duncan A. Mellichamp, Francis J. Doyle

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