Question: 1.1) Consider a model for the log seizure rate that includes the main effects of treatment and time (where time is regarded as a categorical

1.1) Consider a model for the log seizure rate that includes the main effects of treatment and time (where time is regarded as a categorical variable with five levels), and their interaction. Use generalized estimating equations (GEE), assuming separate pairwise correlations among the five responses. Construct a test of the null hypothesis of no effect of treatment on changes in the log seizure rate based on the empirical standard errors. 1.2) What conclusions do you draw about the effect of treatment on changes in the log seizure rate?

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