164. A drug was studied in mice for its hepatotoxicity. The drug was injected into the...

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164. A drug was studied in mice for its hepatotoxicity. The drug was injected into the mice at a dose of 10mg/kg & 20 mg/kg and biopsy from liver was taken. Hepatocytes appeared increased in size vacuoles in cytoplasm with intact nuclei at 10 mg/kg dose and there was loss of nuclei increased in size with vacuoles in the cytoplasm. Which of the following is the correct interpretation of this experiment? a. A. Drug not toxic at 10 mg/kg but toxic at 20 mg/kg. b. B. Drug is equally toxic at both the doses. c. C. Drug is toxic at both doses but toxic at 20 mg/kg. d. D. Drug is not toxic at both the doses. 164. A drug was studied in mice for its hepatotoxicity. The drug was injected into the mice at a dose of 10mg/kg & 20 mg/kg and biopsy from liver was taken. Hepatocytes appeared increased in size vacuoles in cytoplasm with intact nuclei at 10 mg/kg dose and there was loss of nuclei increased in size with vacuoles in the cytoplasm. Which of the following is the correct interpretation of this experiment? a. A. Drug not toxic at 10 mg/kg but toxic at 20 mg/kg. b. B. Drug is equally toxic at both the doses. c. C. Drug is toxic at both doses but toxic at 20 mg/kg. d. D. Drug is not toxic at both the doses.