QUESTION 5 (20 MARKS) The following is a report of a clinical trial to evaluate the...
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QUESTION 5 (20 MARKS) The following is a report of a clinical trial to evaluate the efficiency of maintenance Chemotherapy for acute Leukemia. Patients were randomly allocated to group 1 and II. Group I was the treatment group while Group II was the placebo. The following data on time to replace (weeks-time to remission) were observed. Group 1:9, 13, 13*, 18, 23, 28*, 34, 34, 45*, 48, 50* Group II: 5, 5, 8, 8, 12, 23, 23, 30, 33, 43, 45 (a) (b) Draw the Kaplan Meier curve representing the two sets of data. [6 marks] Find the 95% confidence interval for group I and II, assume the exponential distribution for failure times. [14 marks] QUESTION 5 (20 MARKS) The following is a report of a clinical trial to evaluate the efficiency of maintenance Chemotherapy for acute Leukemia. Patients were randomly allocated to group 1 and II. Group I was the treatment group while Group II was the placebo. The following data on time to replace (weeks-time to remission) were observed. Group 1:9, 13, 13*, 18, 23, 28*, 34, 34, 45*, 48, 50* Group II: 5, 5, 8, 8, 12, 23, 23, 30, 33, 43, 45 (a) (b) Draw the Kaplan Meier curve representing the two sets of data. [6 marks] Find the 95% confidence interval for group I and II, assume the exponential distribution for failure times. [14 marks]
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Practicing Statistics Guided Investigations For The Second Course
ISBN: 9780321586018
1st Edition
Authors: Shonda Kuiper, Jeff Sklar
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