Question: 2. Consider the steady state mass transfer of ascorbic acid into the cytoplasm from the surrounding interstitial fluid through the outer membrane of a cell.

2. Consider the steady state mass transfer of ascorbic acid into the cytoplasm from the surrounding interstitial fluid through the outer membrane of a cell. The mass transfer coefficient on the intracellular space is estimated to be 4.70 x 10 m/s. The mass transfer coefficient outside the cell is approximately 1.9 x 107 m/s. The cellular membrane is 44 A thick, and the partition coefficient, K is 0.50. The diffusivity of ascorbic acid through the cellular membrane is 7.9 x 10 m/s. Assume that the concentration of ascorbic acid inside the cell is at 2.3 yM and in the interstitial space itis 23.5 uM. NOTE: 1.0 pM = 1.0 x 10 moles/liter (M) a. Sketch and label this composite mass transfer problem. (4 points) b. Calculate the flux of ascorbic acid through the cell membrane. (3 points) c. Estimate the size of a cell (make size assumptions clearly) and calculate the rate of removal (flow) of ascorbic acid from the interstitial space. (3 points)

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock blur-text-image

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Law Questions!

2 . Consider the steady state mass transfer of ascorbic acid into the cytoplasm from the surrounding interstitial fluid through the outer membrane of a cell. The mass transfer coefficient on the...

Consider the steady state mass transfer of ascorbic acid into the cytoplasm from the surrounding interstitial fluid through the outer membrane of a cell. The mass transfer coefficient on the...

a. Example 13-1: Batch Reactor with an Exothermic Reaction Wolfram 1. Adiabatic Case: Use Wolfram to see whether you can find a trajectory that is ready to ignite and whose trajectory looks like a...

A 0.008m thick glass door has a thermal conductivity of 0.78W/m.C. The door is 0.8m high and 1.5 m wide. Calculate the steady rate of heat transfer through the door and the temperature of its inner...

We are interested analyzing the diffusion processes associated with the treatment of cancer cells. Consider the experimental system shown in the figure on page 524. A hemispherical clump of cancer...

ANSWER ALL QUESTIONS. WILL GIVE A GOOD RATING FOR A CORRECT ANSWERS ONLY 2-35E A spring whose spring constant is 200 lbf/in has an initial force of 100 lbf acting on it. Determine the work, in Btu,...

Question 1: Fact I: Consider the following setup that follows the standard Solow model in Country A. There are N consumers, each endowed with one unit of available time. Consumers do not value...

1. Consider the Solow model with the production function Y = AF(K,L). Labor force L and productivity factor A are constant unless specifically stated otherwise. Suppose that originally the economy is...

Suppose that you have $1,000 invested in a security that is currently trading at a bid price of $0.99 and an offer price of $1.01. If you were to liquidate your position now, what would the cost of...

If f(x) = x2 + 10 sin x, show that there is a number such that f (c) = 1000.

P20.12 (LO 2, 3, 4) (Lessee-Lessor Entries, Statement of Financial Position Presentation, Finance and Sales-Type Lease) Winston Industries and Ewing SA enter into an agreement that requires Ewing to...

1. Ramierz wants to understand if cognitive behavioral therapy works more effectively with depressed patients than psychodynamic psychotherapy. How would she design an experiment to explore this...